Manchester United’s likely starting lineup against Arsenal in their Premier League opener

Manchester United kick off their 2025/26 Premier League campaign this Sunday (17), at 12:30 p.m. (Brasília time), against Arsenal at Old Trafford. The Red Devils arrive under new management with Rúben Amorim, who begins his first full season in charge, while the Gunners debut their star signing Viktor Gyökeres.
United Start Season With Key Absences
After finishing 15th last season with just 42 points, Manchester United face pressure to respond. However, Amorim will not have a full squad available for the opening clash.
André Onana (goalkeeper) and Lisandro Martínez (defender) are both sidelined due to injury.
These absences force the coach to reshuffle his defense while relying on new signings to add firepower.
Amorim Banks on Reinforcements
Manchester United invested heavily in attack during the transfer window, bringing in Benjamin Šeško, Bryan Mbeumo, and Matheus Cunha. All three are expected to start against Arsenal, signaling Amorim’s intent to rebuild United’s front line.
Likely Starting XI vs Arsenal
- Goalkeeper: Bayindir
- Defense: Yoro, De Ligt, Maguire
- Wing-backs: Diallo, Dorgu
- Midfield: Ugarte, Bruno Fernandes
- Attack: Mbeumo, Matheus Cunha, Šeško
This new-look United will be tested immediately against a side that finished second in the last three Premier League seasons.
Arsenal Maintain Core and Add Gyökeres
Mikel Arteta’s Arsenal arrive with continuity and strength. The Gunners have kept the core that battled for the title and added Viktor Gyökeres, who scored 54 goals in 52 appearances for Sporting. The Swedish striker is set to make his official debut wearing Thierry Henry’s iconic number 14 shirt.
What Comes Next for United
The clash with Arsenal marks the beginning of a tough stretch for Manchester United.
- Aug 24: Fulham (away)
- Aug 27: Grimsby Town (League Cup)
- Aug 30: Burnley (home)
- Sept 14: Manchester derby vs City
For Amorim, Sunday’s opener is more than just three points it is a statement match that could set the tone for United’s season and define how quickly his project takes shape.